AlphaFold Found 2,895 Hidden Protein Links Inside Mitochondria

Texas A&M scientists used Google DeepMind's AlphaFold-Multimer to screen 630,003 possible pairings of about 1,100 human mitochondrial proteins, cataloging 2,895 likely interactions, more than half never reported before. Two years of lab experiments confirmed several of the predicted partnerships in yeast and human cells, and the predictions are published as a free resource called MitoMatch.